Semiconductor technologies have enabled the explosive growth of artificial intelligence (AI). However, as artificial intelligence applications become more widespread and even ubiquitous, their power consumption and consequent CO2 emissions will surge, posing significant sustainability challenges. To address this sustainability crisis, there is a pressing need to enhance the efficiency of information processing and storage. My research program aims to address these challenges through fundamental materials innovation by creating atomically engineered van der Waals materials with quantum mechanical precision, enabling emergent electronic and quantum properties. Our work in fundamental materials science is set to radically transform our understanding and development of van der Waals materials and electronics, leading to paradigm shifts in energy-efficient electronics, including advanced logic devices and memory systems, and to foster breakthroughs in quantum technologies.