Our lab develops methods of protein engineering by directed evolution, with emphasis on creating enzymes that bring new chemical reactions to life. We use evolution augmented with machine learning to circumvent our profound ignorance of how DNA encodes function in order to create new biological molecules.
Our research revolves around studies of colloidal and interfacial phenomena, ranging from fundamental issues related to colloidal interactions to the application of chemically tailored interfaces in chemical and biological sensors. We have designed and synthesized surfactants that incorporate molecular triggers (redox-active and light-sensitive groups) for reversible control of surfactant-based properties of aqueous systems. We are … Continued
My research group focuses on the development of bioactive and bioresponsive materials that can be used as cell culture systems. Specifically, we design synthetic biomaterials that capture key features of the unique chemistry and physical properties of a cell’s niche—an environment that is not only tissue specific, but can be strikingly heterogeneous and dynamic. Unique … Continued