The long-term goal of our research is to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation. In this broad research area, we are specifically interested in the molecular underpinnings of activity-dependent regulation of synaptic strength, the … Continued
All sensory perception and every movement, as well as feelings, memories and motivation, arise from the bustling activity of many millions of interconnected cells in the nervous system. The ultimate function of this elaborate network is to generate behavior. My research seeks to understand how animal brains transform sensory information and internal state into fine-tuned … Continued
My research focuses on the molecular mechanisms of memory storage and the molecular basis of neurodevelopmental and psychiatric disorders. My group has pioneered the use of molecular and genetic approaches to define how neural circuits mediate behavior, including identifying the molecular impact of sleep deprivation on neuronal function and the role of epigenetic mechanisms in … Continued